作者：马冉1 ，江倩1 ，顾莹莹1 ，王欣璐2 ，陈扬航1 ，沈毅1 ，王涛1 ，洪城1 ，郭文亮1 ，王健1 ，张挪富1 ，刘春丽1

单位：

1.510120广东省广州市，广州医科大学附属第一医院呼吸内科 广州呼吸健康研究院 呼吸疾病国家重点实验 室 国家呼吸系统疾病临床医学研究中心　2.510120广东省广州市，广州医科大学附属第一医院核医学科

Units：

1.Department of Respiratory Medicine, the First Affiliated Hospital of Guangzhou Medical University/Guangzhou Institute of Respiratory Health/State Key Laboratory of Respiratory Diseases/National Clinical Research Center for Respiratory Disease, Guangzhou 510120, China 2.Department of Nuclear Medicine, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China

关键词：

肺栓塞；肺肿瘤；肿瘤转移；绒毛膜上皮癌；病例报告

Keywords：

Pulmonary embolism; Lung neoplasms; Neoplasm metastasis; Choriocarcinoma; Case reports

CLC：

R 563.5 R 734.2

DOI：

10.12114/j.issn.1008-5971.2023.00.325

Funds：

呼吸疾病国家重点实验室自主课题项目 （ SKLRD-Z-202313 ）；广东省自然科学基金面上项目 （2023A1515010443）；广州市科学技术局市校（院）联合资助项目 （202201020401）

摘要：

绒毛膜上皮癌（CCA）是一种恶性滋养细胞肿瘤，多由胚胎时期原始生殖细胞异常分化导致，常发生 于性腺部位，常出现肺转移，进而增加肺动脉高压和肺栓塞发生风险。本文报道1例罕见的以肺栓塞为表现的CCA肺 转移患者，其为中年女性，肿瘤病灶位于右肺动脉干，经皮肺动脉腔内组织活检病理检查证实为CCA肺转移。同时笔 者对相关文献进行总结，以提高临床医生对该病的诊治水平。

Abstract：

Choriocarcinoma (CCA) is one of the malignant tumors of reproductive origin, which is often caused by abnormal differentiation of primordial germ cells in the embryonic stage, it often occurs in the gonad and often occurs pulmonary metastasis, and then increases the risk of pulmonary hypertension and pulmonary embolism. This article reports a rare case of lung metastasis of CCA characterized by pulmonary embolism. The patient is a 46 year old female with a tumor lesion located in the right pulmonary artery trunk. Percutaneous pulmonary artery tissue biopsy pathology confirmed lung metastasis of CCA. At the same time, the author summarize the relevant literature to improve the clinical diagnosis and treatment level of the disease.

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