作者：卢俊伟1 ，常傲然1 ，胡慧敏1 ，李洁莉1 ，王红红2

单位：

1.430071湖北省武汉市，武汉大学中南医院神经外科　2.410013湖南省长沙市，中南大学 湘雅护理学院

Units：

1.Department of Neurosurgery, Zhongnan Hospital of Wuhan University, Wuhan 430071, China 2.Xiangya School of Nursing, Central South University, Changsha 410013, China

关键词：

脑肿瘤；衰弱；认知障碍；综述

Keywords：

Brain neoplasms; Frality; Cognitive dysfunction; Review

CLC：

R 739.41

DOI：

10.12114/j.issn.1008-5971.2024.00.039

Funds：

武汉大学中南医院临床护理研究项目 （LCHLYJ202308）；中西医结合护理学术能力提升工程专项基金项 目（ZXYJHHL-K-2023-M19）

摘要：

　颅脑肿瘤由于发病位置不同，其表现症状也不尽相同，且患者常伴有机体功能的衰退。衰弱作为肿瘤 患者常见的伴随症状，在颅内肿瘤术后患者中高发，其在降低患者生存质量的同时，还会导致患者认知功能下降、治 疗费用增加、术后并发症增多、住院时间延长甚至死亡。颅脑肿瘤患者和衰弱患者均可出现认知功能下降，医务人员 需将颅脑肿瘤侵犯功能区等原因导致的认知障碍与患者本身存在的认知衰弱相鉴别，从而对患者进行精准干预，以改 善其认知功能。本文通过回顾既往文献，首先分析了衰弱对颅脑肿瘤患者认知功能及预后的影响，然后分析了颅脑肿 瘤患者发生衰弱的危险因素，最后分析了颅脑肿瘤导致的认知障碍与认知衰弱的主要区别，指出临床医务人员应尽早 识别伴有衰弱的颅脑肿瘤患者，并精准辨别其认知功能下降的原因，从而对其进行精准干预，进而改善其预后。

Abstract：

Due to the different locations of onset, the symptoms and manifestations of cranial tumors vary, and patients often experience functional decline. Frailty, as a common accompanying symptom of tumor patients, is highly prevalent in postoperative intracranial tumor patients. While it reduces the quality of life of patients, it can also lead to cognitive decline, increased treatment costs, increased postoperative complications, prolonged hospital stay, and even death. Both patients with cranial tumor and patients with frailty can have cognitive function decline. Medical personnel need to distinguish cognitive impairment caused by brain tumor invasion of functional areas from the patients' own cognitive frailty, so as to carry out precise intervention for patients to improve their cognitive function. By reviewing the previous literature, this paper first analyzed the effects of frailty on cognitive function and prognosis of patients with cranial tumor, then analyzed the risk factors of frailty in patients with cranial tumor, and finally analyzed the main differences between cognitive impairment caused by cranial tumor and cognitive frailty, and pointed out that clinical medical personnel should identify patients with cranial tumor accompanied by frailty as early as possible, and accurately identify the reasons for their cognitive decline, so as to provide precise intervention and improve their prognosis.

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