作者：吴文娜 ，秦瑶 ，周晓阳 ，王晓君 ，张烈民，彭春燕，彭好

单位：

1.430070湖北省武汉市，湖北省妇女儿童医院 华中科技大学同济医学院附属湖北妇幼保健院成人内科　2.430060湖北 省武汉市，武汉大学人民医院心血管内科

Units：

1.Department of Adult Internal Medicine, Women and Children's Hospital of Hubei Province/Maternal and Child Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430070, China 2.Department of Cardiovascular Medicine, Renmin Hospital of Wuhan University, Wuhan 430060, China

关键词：

静脉血栓栓塞；妊娠并发症；诊断；治疗；预防策略

Keywords：

Venous thromboembolism; Pregnancy complications; Diagnosis; Therapy; Prevention strategy

CLC：

R 619.2

DOI：

10.12114/j.issn.1008-5971.2023.00.317

Funds：

国家自然科学基金资助项目（81970331）

摘要：

妊娠相关静脉血栓栓塞（VTE）是西方国家及我国孕产妇死亡的主要原因之一，主要包括深静脉血栓 形成和肺栓塞。研究表明，妊娠期和产褥期女性VTE发生风险明显高于非妊娠期女性，故准确诊断妊娠相关VTE并采 取相应措施是减少孕产妇死亡的重要手段。但考虑胎儿和母体健康，使妊娠相关VTE的诊断、治疗和预防变得复杂。 本文对妊娠相关VTE的流行病学、发病机制、危险因素、临床症状、诊断、治疗、围生期管理及预防策略多个方面进 行阐述，以期提高临床医生对妊娠相关VTE的诊疗水平，进而改善母婴结局。

Abstract：

Pregnancy-related venous thromboembolism (VTE) is one of the main causes of maternal death in western countries and China, mainly including deep vein thrombosis and pulmonary embolism. Studies have shown that the risk of VTE in pregnant and puerperal women is significantly higher than that in non-pregnant women. Therefore, accurate diagnosis of pregnancy-related VTE and corresponding prevention and treatment measures are important means to reduce maternal death. However, because of the consideration of fetal and maternal health, the diagnosis, treatment, and prevention of pregnancy related VTE become complicated. This article reviews the epidemiology, pathogenesis, risk factors, clinical symptoms, diagnosis, treatment, perinatal management and prevention strategy of pregnancy-related VTE, in order to improve the diagnosis and treatment level of pregnancy-related VTE of clinicians and then improve the maternal and infant outcomes.

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