作者：尚红彦，陈旦旦，邓庆梅，焦丽，马祖长

单位：

1.230088安徽省合肥市，中国科学院合肥肿瘤医院肺 部肿瘤中心 2.230088安徽省合肥市，中国科学院合肥肿瘤医院护理部 3.230088安徽省合肥市，中国科学院合肥肿瘤医院检验中心 4.230031安徽省合肥市，中国科学院合肥物质科学研究院

Units：

1.Department of Lung Cancer Center, Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei 230088, China 2.Department of Nursing, Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei 230088, China 3.Department of Laboratory Center, Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei 230088, China 4.Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China

关键词：

睡眠呼吸暂停，阻塞性；睡眠呼吸暂停低通气综合征；肥胖症；减重干预；综述

Keywords：

Sleep apnea, obstructive; Sleep apnea hypopnea syndrome; Obesity; Weight loss intervention; Review

CLC：

R 563.8 R 589.25

DOI：

10.12114/j.issn.1008-5971.2023.00.234

Funds：

安徽省重点研究与开发计划项目 （202004h07020017）；中国科学院合肥肿瘤医院优秀医学青年人才 计划项目（YQJH2021011）

摘要：

肥胖型阻塞性睡眠呼吸暂停低通气综合征是一种潜在的致死性疾病，由于肥胖是其最重要的可逆性危 险因素，减重干预是其最基础且最重要的治疗手段。本文通过回顾相关文献，总结了目前关于肥胖型阻塞性睡眠呼吸 暂停低通气综合征的减重干预手段〔包括非手术干预（饮食干预、运动干预、知信行干预、持续气道正压通气治疗、 减重药物治疗、中医疗法）、手术干预（减重代谢手术）〕及其实际应用效果，并指出目前缺少明确的操作流程，相 关研究样本量较少，且研究结论存在争议，急需搭建一个关于肥胖型阻塞性睡眠呼吸暂停低通气综合征患者减重干预 的多学科团队协作平台。

Abstract：

Obese obstructive sleep apnea hypopnea syndrome is a potentially fatal disease. Since obesity is its most important reversible risk factor, weight loss intervention is its most basic and most important treatment. Through reviewing relevant literature, this article summarizes the current weight reduction interventions [including non-surgical interventions (diet intervention, exercise intervention, knowledge, belief and practice intervention, continuous positive airway pressure treatment, anti-obesity pharmacotherapy, Chinese medicine therapy) , surgical interventions (weight loss metabolic surgery) ] and their practical application effects on obese obstructive sleep apnea hypopnea syndrome, and points out that there is a lack of clear operational process, the number of relevant research samples is small, and the research conclusions are controversial, so there is an urgent need to build a multidisciplinary team collaboration platform on weight loss intervention for patients with obese obstructive sleep apnea hypopnea syndrome.

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