作者：石曼欣妤，耿雨涵，杨静，曹洪丽

单位：

1.首都医科大学北京康复医学院2.解放军总医院第一医学中心康复医学科3.山东省立第三医院药剂科4.首都医科大学附属北京康复医院急救医学中心

Units：

Beijing Rehabilitation Medical College, Capital Medical University;Department of Rehabilitation Medicine, First Medical Center, PLA General Hospital;Department of Pharmacy, Shandong Provincial Third Hospital;Emergency Medical Center, Beijing Rehabilitation Hospital, Capital Medical University;

关键词：

哮喘; 肠道微生态; 发病机制; 发展过程; 综述;

Keywords：

Asthma;Intestinal microecology;Pathogenesis;Development process;Review;

CLC：

DOI：

10.12114/j.issn.1008-5971.2022.00.311

Funds：

2020年山东省医学会治疗药物监测科研基金（YXH2020ZX047）；

摘要：

近年来，随着对微生物生态学的理解，人们逐渐认识到微生物群落在维持人类健康方面有着重要作用。肠道为人体中最大的微生物群提供环境，当肠道微生态失衡时，不仅对肠道系统产生影响，也会影响其他器官。研究表明，在支气管哮喘的进展过程中，肠道微生物群对疾病有一定影响。本文通过对人体微生态学的研究进展、肠道微生态与支气管哮喘发病机制及肠道微生态与支气管哮喘发展的关系进行综述，旨在为支气管哮喘的预防和治疗方向提供新思路。

Abstract：

In recent years, with the understanding of microbial ecology, people gradually realize that microbial communities play an important role in maintaining human health. The gut provides an environment for the largest microbiome in the human body. When the gutmicroecology is out of balance, it not only affects its own system, but also affects other organs. The research suggests that during the progression of bronchial asthma, the gut microbiome has some influence on the disease. This article summarizes and analyzes the research progress of human microecology, the pathogenesis of intestinal microecology and bronchial asthma, and the correlation between intestinal microecdogy and the occurrence and development of bronchial asthma, aiming to provide new ideas for the prevention and treatment of bronchial asthma.

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