作者：魏爱芹1，郭晓敏2

单位：

1.710021陕西省西安市，西安医学院2.710068陕西省西安市，陕西省人民医院神经内科

Units：

1.Xi'an Medical University, Xi'an 710021, China2.Department of Neurology, Shaanxi Provincial People's Hospital, Xi'an 710068, China

关键词：

脑炎；自身免疫性脑炎；抗Amphiphysin抗体；非惊厥性癫痫持续状态；病例报告

Keywords：

Encephalitis; Autoimmune encephalitis; Anti-Amphiphysin antibody; Nonconvulsive status epilepticus;Case reports

CLC：

　R 512.31　

DOI：

10.12114/j.issn.1008-5971.2022.00.258

Funds：

陕西省重点研发计划项目（S2020-YF-YBSF-0260）

摘要：

自身免疫性脑炎类型较多，但抗Amphiphysin抗体相关自身免疫性脑炎在临床上少见。抗Amphiphysin抗体相关自身免疫性脑炎患者主要表现为癫痫发作、认知功能下降、精神异常等，但以非惊厥性癫痫持续状态为主要表现的患者较少。本文报道陕西省人民医院收治的1例以非惊厥性癫痫持续状态为主要表现的抗Amphiphysin抗体相关自身免疫性脑炎患者的诊疗经过，并进行相关文献复习，以加强临床医生对该病的认识。

Abstract：

There are many types of autoimmune encephalitis, but anti-Amphiphysin antibody-related autoimmuneencephalitis is rare in clinical practice. Anti-Amphiphysin antibody-related autoimmune encephalitis patients mainly manifestedas epileptic seizures, cognitive decline, mental disorders, etc., but the patients with non-convulsive status epilepticus were less.This article reports the diagnosis and treatment of a patient with anti-Amphiphysin antibody-related autoimmune encephalitiswith non-convulsive status epilepticus as the main manifestation in Shaanxi Provincial People's Hospital, and reviews the relevantliterature to strengthen clinicians' understanding of the disease.

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