作者：李漪，蒋和俊，周胜华，陈鹏飞，苏文，金权，刘朝硕

单位：

410011湖南省长沙市，中南大学湘雅二医院心血管内科

Units：

Department of Cardiovascular Medicine, the Second Xiangya Hospital of Central South University, Changsha 410011, China

关键词：

冠心病；牙龈出血；经皮冠状动脉介入治疗；影响因素分析

Keywords：

Coronary disease; Gingival hemorrhage; Percutaneous coronary intervention; Root cause analysis

CLC：

R 541.4　R 781.41

DOI：

10.12114/j.issn.1008-5971.2022.00.277

Funds：

国家自然科学基金面上项目（81870258）

摘要：

　目的　探讨冠心病患者PCI后发生牙龈出血的影响因素。方法　选取2021年10月至2022年1月中南大学湘雅二医院收治的接受PCI的冠心病患者240例。根据患者术后72 h内牙龈出血（包括进食硬食物时出血、刷牙出血、自行出血）发生情况将其分为出血组与未出血组。观察患者术后72 h内牙龈出血发生率。通过单因素、多因素Logistic回归分析探讨冠心病患者PCI后发生牙龈出血的影响因素。结果　240例患者中37例发生牙龈出血，发生率为15.4%。多因素Logistic回归分析结果显示，肾功能不全〔OR =9.255，95%CI （1.487，57.613）〕与手术时长〔OR =1.010，95%CI （1.001，1.020）〕是冠心病患者PCI后发生牙龈出血的影响因素（P ＜0.05）。结论　慢性肾功能不全和手术时长是冠心病患者PCI后发生牙龈出血的影响因素。

Abstract：

Objective　To investigate the influencing factors of gingival hemorrhage in patients with coronary heartdisease after PCI. Methods　A total of 240 patients with coronary heart disease who received PCI from October 2021 to January2022 in the Second Xiangya Hospital of Central South University were selected. The patients were divided into bleeding groupand non-bleeding group according to the occurrence of gingival hemorrhage (including bleeding when eating hard food, bleedingwhen brushing teeth and spontaneous bleeding) at 72 hours after operation. The incidence of gingival hemorrhage at 72 hoursafter operation was observed. Univariate and multivariate Logistic regression analysis was used to explore the influencing factorsof gingival hemorrhage after PCI in patients with coronary heart disease. Results　Gingival hemorrhage occurred in 37 of 240patients, and the incidence was 15.4%. The results of multivariate Logistic regression analysis showed that renal insufficiency[OR =9.255, 95%CI (1.487, 57.613) ] and operation time [OR =1.010, 95%CI (1.001, 1.020) ] were the influencing factors ofgingival hemorrhage after PCI in patients with coronary heart disease (P < 0.05) . Conclusion　Renal insufficiency and operationtime are the influencing factors of gingival hemorrhage after PCI in patients with coronary heart disease.

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