作者：贾志毅，张浩，李文静，韩清梅，孙蓉，刘玉胜，邝江莹，鹿庆华

单位：

1.250033山东省济南市，山东大学第二医院心血管内科 2.250033山东省济南市，山东大学第二医院基础医学研究所 通信作者：邝江莹，E-mail：710887707@qq.com 鹿庆华，E-mail：lqhzhy@163.com

Units：

1.Department of Cardiology, the Second Hospital of Shandong University, Jinan 250033, China 2.Institute of Basic Medical Sciences, the Second Hospital of Shandong University, Jinan 250033, China Corresponding author: KUANG Jiangying, E-mail: 710887707@qq.com LU Qinghua, E-mail: lqhzhy@163.com

关键词：

应激性心肌病; Takotsubo综合征; 临床特征; 病理生理学; 诊断; 治疗; 综述;

Keywords：

Stress cardiomyopathy; Takotsubo syndrome; Clinical features; Pathophysiology; Diagnosis; Treatment;Review

CLC：

DOI：

10.12114/j.issn.1008-5971.2022.00.148

Funds：

山东省自然科学基金面上项目（ZR2020MH042）；临床科学家菁英培训计划优秀临床研究方案基金（20170703）

摘要：

应激性心肌病（SC）是一种急性可逆性心力衰竭综合征，好发于绝经期女性，大多数患者在发病前遭受过心理或生理的应激刺激，临床表现与急性冠脉综合征患者相似。目前该病确切的发病机制尚未明确，可能由几个不同途径单独或协同作用导致。由于SC诊断率的逐年提升，人们对该病的认识也不断深入，本文就SC的流行病学、触发因素和易感因素、病理生理学、临床特征、诊断、治疗、预后进行综述，以提高临床对该病的认识。

Abstract：

【Abstract】 Stress cardiomyopathy (SC) is an acute reversible heart failure syndrome. It tends to occur in menopausalwomen, most patients have suffered psychological or physiological stress before onset, the clinical manifestations were similar tothose of patients with acute coronary syndrome. At present, the exact pathogenesis of the disease is not clear, it may be causedby the single or synergistic action of several different pathophysiological pathways. As the diagnostic rate of SC increases yearby year, people's understanding of the disease is also deepening. This paper reviews the epidemiology, trigger factors andsusceptibility factors, pathophysiology, clinical characteristics, diagnosis, treatment and prognosis of SC, in order to improve theclinical understanding of the disease.

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