作者：周笋，董长征，刘星，曹姗

单位：

1.075000河北省张家口市，河北北方学院研究生院 2.050051河北省石家庄市，河北省人民医院神经外二科 通信作者：董长征，E-mail：sjwek2018@sina.com

Units：

1.Graduate Faculty, Hebei North University, Zhangjiakou 075000, China 2.Second Department of Neurosurgery, Hebei General Hospital, Shijiazhuang 050051, China Corresponding author: DONG Changzheng, E-mail: sjwek2018@sina.com

关键词：

耐药性癫痫; 难治性癫痫; 立体定向脑电图; 术前评估;

Keywords：

Drug resistant epilepsy; Intractable epilepsy; Stereoelectroencephalography; Preoperative evaluation

CLC：

DOI：

10.12114/j.issn.1008-5971.2022.00.121

Funds：

摘要：

癫痫是一种严重的慢性神经系统疾病，其治疗重点在于控制患者癫痫发作。大多数患者口服抗癫痫药物即可有效缓解病情，但对于难治性癫痫患者来说，口服抗癫痫药物往往不能有效控制癫痫发作，需进一步手术切除致痫区域。立体定向脑电图（SEEG）检查是一项安全有效的侵入性术前评估方法，在难治性癫痫患者致痫灶的精确定位及治疗方面具有重要作用。本文简述了SEEG电极植入术、SEEG检查结果分析、SEEG电极植入术的优缺点、SEEG引导下射频热凝损毁术、SEEG电极植入方案的规划及具体应用，以期深入、全面地了解SEEG在难治性癫痫患者术前评估中的应用价值。

Abstract：

【Abstract】 Epilepsy is a serious chronic disease of nervous system and the key point of treatment is to keep theepilepsy attack under control. Most patients can effectively relieve the illness by oral antiepileptic drugs, but patients withintractable epilepsy cannot be effectively controlled, who need further surgical removal of the epileptic region to reduce theseizures. Stereoelectroencephalography (SEEG) is a safe and effective invasive preoperative evaluation method, which plays animpaortant role in the accurate localization and treatment of epileptogenic foci in patients with intractable epilepsy. This paperbriefly describes SEEG electrode implantation, analysis of SEEG examination results, advantages and disadvantages of SEEGelectrode implantation, SEEG-guided radio frequency thermocoagulation, planning and specific application of SEEG electrodeimplantation scheme, in order to deeply and comprehensively understand the application value of SEEG in preoperative evaluationof patients with intractable epilepsy.

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