作者：邢莎莎1，商鲁翔2，刘振东3

单位：

1.250100 山东省济南市历下区第三人民医院内科　 2.250014 山东省济南市，山东第一医科大学第一附属医院 山东 省千佛山医院心血管病学 山东省医药卫生心律失常重点实验室 3.250062 山东省济南市，山东第一医科大学 山东省医学科学院 基础医学研究所

Units：

1.Department of Internal Medicine, Lixia No.3 People's Hospital, Jinan 250100, China 2.Department of Cardiology, the First Affiliated Hospital of Shandong First Medical University/Shandong Provincial Qianfoshan Hospital/Shandong Medicine and Health Key Laboratory of Cardiac Electrophysiology and Arrhythmia, Jinan 250014, China 3.Institute of Basic Medicine, Shandong First Medical University/Shandong Academy of Medical Sciences, Jinan 250062, China

关键词：

心力衰竭；糖尿病；心脏再同步疗法；预后；综述

Keywords：

Heart failure; Diabetes mellitus; Cardiac resynchronization therapy; Prognosis; Review

CLC：

R 541.62　R 587.1

DOI：

10.12114/j.issn.1008-5971.2021.00.136

Funds：

国家自然科学基金资助项目（81670432）

摘要：

心脏再同步化治疗（CRT）是针对伴有心脏非同步收缩的心力衰竭患者的有效治疗方法，其疗效受多 种临床因素影响。本文围绕糖尿病这一常见危险因素及临床合并症进行分析，叙述了合并糖尿病对心力衰竭患者CRT 植入术后预后的影响，并简述了心力衰竭合并糖尿病患者不良预后的预测因素以及改善该部分患者CRT 植入术后预后 的措施，以期为合并糖尿病的心力衰竭患者CRT 植入术前筛选及术后综合治疗提供参考。

Abstract：

　Cardiac resynchronization therapy (CRT) is an effective treatment method for patients with heart failure (HF) accompanied by unsynchronized cardiac contractions, and its efficacy is affected by a variety of clinical factors. This article discusses the influence of diabetes, a common risk factor and clinical complication, on the prognosis of HF patients after CRT implantation, and briefly describes the predictors of poor prognosis of patients with HF and diabetes and the measures to improve the prognosis of these patients after CRT implantation, in order to provide reference for preoperative screening and postoperative comprehensive treatment of CRT implantation in patients with HF and diabetes.

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