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2024-5-25
Vol 32, issue 5

ISSUE

2020 年5 期 第28 卷

前沿进展 HTML下载 PDF下载

γ- 谷氨酰转移酶与心血管疾病相关性的研究进展

Research progress on the relationship of gamma-glutamyl transferase and cardiovascular diseases

作者:任懿1 ,尹伶 2

单位:
1.430000 湖北省武汉市,武汉科技大学附属天佑医院;2.430000 湖北省武汉市,武汉科技大学;通信作者:尹伶,E-mail:1500252626@qq.com
关键词:
心血管疾病;γ- 谷氨酰转移酶;相关性;综述
Keywords:
Cardiovascular disease;Gamma-glutamyl transferase;Correlation;Review
CLC:
R 541.6
DOI:
DOI:10.3969/j.issn.1008-5971.2020.05.021
Funds:

摘要:

γ- 谷氨酰转移酶(GGT)是谷胱甘肽代谢过程中的关键酶之一,广泛分布于人体各组织器官中,主要参与细胞氧化还原调控、炎性反应等过程。近年来大量的研究证明了血清 GGT 水平升高与高血压、冠心病、脑卒中、心律失常等心血管疾病(CVD)相关,本文简述了血清 GGT 水平与 CVD 相关性,指出血清 GGT 水平与 CVD 发生、发展及患者预后密切相关。

Abstract:

Gamma-glutamyl transferase(GGT),as one of the key enzymes in glutathione metabolism,is widelydistributed in various tissues and organs of human body,and GGT is involved in cell redox regulation,inflammation and so on.Inrecent years,a large number of studies have proved that,the increasing of serum GGT is related to cardiovascular diseases (CVD)such as hypertension,coronary heart disease,stroke,arrhythmia.This paper reviewed the research progress on the relationshipof serum GGT and CVD,and pointed out that serum GGT level was closely related to the occurrence and development of CVDand the prognosis of patients.

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