作者：杨燕，吴远华，蔡静，曹丽平

单位：

1.贵州中医药大学2.贵州中医药大学第一附属医院神经内科

单位（英文）：

1.Guizhou University of Traditional Chinese Medicine, Guiyang 550002, China 2.Department of Neurology, the First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang 550001, China

关键词：

特鲁索综合征; 脑梗死; 低分子肝素; 通窍化栓汤; 病例报告;

关键词（英文）：

Trousseau syndrome; Brain infarction; Low molecular weight heparin; Tongqiao Huashuan decoction; Case reports

中图分类号：

DOI：

10.12114/j.issn.1008-5971.2023.00.066

基金项目：

贵州省优秀科技教育人才省长专项资金项目（2010144）； 贵州省中药现代化科技产业研究开发专项项目（20125024）； 贵阳市科技计划项目（2011204）； 贵州中医药大学科研项目（3040-040210134）；

摘要：

特鲁索综合征是临床上较为少见的恶性疾病，其特征是血液呈高凝状态，进而引起动脉栓塞并伴有脑梗死。目前，抗凝治疗是特鲁索综合征的主要治疗手段，但患者脑梗死复发风险可能较高，且长期使用抗凝剂可增加患者出血风险。本文报道了3例采用低分子肝素联合通窍化栓汤治疗的特鲁索综合征伴急性脑梗死患者的诊疗过程，患者均预后较好，这为临床医生治疗特鲁索综合征伴急性脑梗死提供了一定经验、借鉴。

英文摘要：

Trousseau syndrome is a rare malignant disease in clinic. It is characterized by hypercoagulability of blood, which leads to arterial embolism and cerebral infarction. At present, anticoagulant therapy is the main treatment for Trousseau syndrome, but the risk of recurrence of cerebral infarction may be high, and long-term use of anticoagulants can increase the risk of bleeding. This paper reports three cases of patients with Trousseau syndrome complicated with acute cerebral infarction who treated with low molecular weight heparin combined with Tongqiao Huashuan decoction. All patients had good prognosis, this provides some experience and reference for clinicians in the treatment of patients with Trousseau syndrome complicated with acute cerebral infarction.

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