作者：王聪1，刘富强2，王军奎2

单位：

1.710068陕西省西安市，西安医学院2.710068陕西省西安市，陕西省人民医院心血管内科

单位（英文）：

1.Xi'an Medical University, Xi'an 710068, China2.Department of Cardiology, Shaanxi Provincial People's Hospital, Xi'an 710068, China

关键词：

肠道菌群；吸烟；综述

关键词（英文）：

Intestinal flora; Smoke; Review

中图分类号：

R 378.2

DOI：

10.12114/j.issn.1008-5971.2022.00.232

基金项目：

摘要：

吸烟会导致肠道菌群发生改变。香烟烟雾中的有毒物质可以改变肠道菌群的丰度及多样性，其机制包括改变肠道菌群赖以生存的内环境、调节宿主病理、引起优势菌比例失衡等，导致肠道酸碱失衡、氧化应激及免疫系统破坏，从而引起肠道疾病及全身性疾病。本文主要综述了吸烟及香烟烟雾中的有毒物质对肠道菌群的影响，以期为控烟及相关疾病的防治提供参考依据。

英文摘要：

Smoking can cause changes in the intestinal flora. The toxic substances in cigarette smoke can change the abundance and diversity of intestinal flora, the mechanism including changing the internal environment for the survival ofintestinal flora, regulating host pathology, causing imbalance of the proportion of dominant bacteria and so on, leading to intestinal acid-base imbalance, oxidative stress, immune system damage, thus causing intestinal diseases and systemic diseases. This paper mainly summarizes the impact of smoking and toxic substances in cigarette smoke on intestinal flora, in order to provide reference for control smoking, prevention and treatment of related diseases.

参考文献：