2020 年4 期 第28 卷
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碎片状 QRS 波与高血压患者室性心律失常发生的关系研究
Relationship between fragmented QRS waves and ventricular arrhythmia in patients withhypertension
作者:孙更新,王西辉
- 单位:
- 710038 陕西省西安市,西安医学院第二附属医院;通信作者:王西辉,E-mail:3261826584@qq.com
- 关键词:
- 高血压;心律失常;心电图;碎片状 QRS 波;影响因素分析
- 关键词(英文):
- Hypertension;Arrhythmia;Electrocardiogram;Fragmented QRS wave;Root cause analysis
- 中图分类号:
- R 544.1 R 541.7
- DOI:
- DOI:10.3969/j.issn.1008-5971.2020.04.005
- 基金项目:
- 陕西省重点研发计划项目(2018SF-114)
摘要:
背景 高血压患者室性心律失常的发生率近年来不断增高,但目前仍无有效的预测指标。目的 分析碎片状 QRS 波与高血压患者室性心律失常发生的关系。方法 选取 2017 年 6 月—2019 年 6 月于西安医学院第二附属医院就诊的高血压患者 246 例,根据心电图将发生室性心律失常患者分为试验组(n=62),未发生室性心律失常患者为对照组(n=184)。比较两组患者一般资料、高血压分级、实验室检查指标、心电图特征(包括有无 P 波缩短、PR间期异常、碎片状 QRS 波、QRS 波延长和 ST 段异常),采用多因素 Cox 风险比例回归分析碎片状 QRS 波与高血压患者室性心律失常发生的关系。结果 两组患者有无 P 波缩短、PR 间期异常、QRS 波延长、ST 段异常比较,差异无统计学意义(P>0.05),试验组患者碎片状QRS波发生率高于对照组(P<0.05)。多因素Cox风险比例回归分析结果显示,碎片状 QRS 波是高血压患者室性心律失常发生的影响因素〔HR=3.431,95%CI(1.502,7.835),P<0.05〕。结论碎片状 QRS 波是高血压患者室性心律失常的影响因素,可于临床上对高血压患者室性心律失常的风险进行预测。
英文摘要:
Background In recent years,the incidence of ventricular arrhythmia in patients with hypertension hasbeen increasing,but there is no effective predictor.Objective To analysis the relationship between fragmented QRS waves andventricular arrhythmia in patients with hypertension.Methods A total of 246 hypertensive patients were admitted to SecondAffiliated Hospital of Xi'an Medical College from June 2017 to June 2019,they were divided into experimental groups (heppenedventricular arrhythmia,n=62) and control group(no ventricular arrhythmia,n=184) according to electrocardiogram.General data,hypertension grade,laboratory examination index and ECG characteristics(including P-wave shortening,PRinterval abnormality,fragmentary QRS wave,QRS wave prolongation and ST segment abnormality) compared between thetwo groups.Multivariate Cox risk ratio regression was used to analyze the relationship between fragmented QRS and ventriculararrhythmia in hypertensive with patients.Results There was no statistically significant difference in P-wave shortening,PRinterval abnormality,QRS wave extension or ST segment abnormalities between the two groups(P>0.05),but the incidenceof fragmentary QRS wave in experimental groups was higher than that in control group(P<0.05). Multivariate Cox risk ratioregression analysis showed that,fragmentary QRS wave was independent influencing factors of ventricular arrhythmia in patientswith hypertension〔HR=3.431,95%CI(1.502,7.835),P<0.05〕.Conclusion Fragmented QRS waves have a significantcorrelation with the risk of ventricular arrhythmia in patients with hypertension,and can be used to predict the risk of ventriculararrhythmia in patients with hypertension.
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