作者：熊明秀1，2 ，张静2

单位：

1.610054四川省成都市，电子科技大学医学院　2.610072四川省成都市，四川省医学科学院 四川省人民医院呼吸与危重症医学科

Units：

1.School of Medicine UESTC, Chengdu 610054, China 2.Department of Respiratory and Critical Care Medicine, Sichuan Academy of Medical Sciences·Sichuan Provincial People's Hospital, Chengdu 610072, China

关键词：

静脉血栓栓塞；癌基因；驱动基因；综述

Keywords：

Venous thromboembolism; Oncogenes; Driver gene; Review

CLC：

R 619.2

DOI：

10.12114/j.issn.1008-5971.2024.00.040

Funds：

四川省科技厅重点研发项目（2022YFS0107）；四川 省医学会青年创新基金项目（S19011）

摘要：

静脉血栓栓塞（VTE）是恶性肿瘤患者的常见并发症之一，其是肿瘤患者的第二大死亡原因，而肿瘤 自身复杂性导致肿瘤相关VTE的危险因素多样。近年随着基因二代测序技术发展，越来越多研究表明，肿瘤驱动基因 可参与VTE的发生发展。基于此，本文主要综述了肿瘤驱动基因与VTE关系的研究进展，以期为肿瘤相关VTE的预防 和治疗提供新思路。

Abstract：

Venous thromboembolism (VTE) is one of the common complications in patients with malignant tumors, and it is the second leading cause of death in cancer patients. The complexity of the tumor itself leads to various risk factors for tumor related VTE. In recent years, with the development of next-generation sequencing technology, more and more studies have shown that tumor driver genes can participate in the occurrence and development of VTE. Based on this, this article mainly reviews the research progress of the relationship between tumor driver genes and VTE, in order to provide new ideas for the prevention and treatment of tumor-related VTE.

ReferenceList：