作者：于泽宁，陈清杰，杨毅宁

单位：

1.830054新疆维吾尔自治区乌鲁木齐市，新疆医科大学第一附属医院心脏中心　2.830001新疆维吾尔自治区乌鲁木齐市，新疆维吾尔自治区人民医院心内科

单位（英文）：

1.Heart Center, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China2.Department of Cardiology, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, China

关键词：

　斑块，动脉粥样硬化；分层斑块；冠状动脉；光学相干断层成像；综述

关键词（英文）：

Plaque, atherosclerotic; Layered plaque; Coronary artery; Optical coherence tomography; Review

中图分类号：

DOI：

基金项目：

新疆维吾尔自治区高校科研计划（XJEDU2021I015）

摘要：

急性冠脉综合征（ACS）常由斑块破裂或斑块侵蚀继发血栓形成，堵塞冠状动脉并导致血流急性中断引起的。但由于内皮-抗栓系统的存在，部分斑块破裂或血栓被机化后进行修复并形成冠状动脉分层斑块，但未造成急性缺血事件。由此可见，冠状动脉分层斑块代表了先前斑块的不稳定特征。光学相干断层成像（OCT）是一种高分辨率、可在体识别冠状动脉分层斑块的腔内影像学技术。本文主要综述了冠状动脉分层斑块的病理学特征、腔内影像学表现、临床特征及治疗策略，旨在提高临床医生对冠状动脉分层斑块的认识。

英文摘要：

　Acute coronary syndrome (ACS) is often caused by plaque rupture or plaque erosion secondary tothrombosis, blocking the coronary artery and leading to acute interruption of blood flow. However, due to the existence of theendothelial-antithrombotic system, some plaques rupture or thrombus are organized and repaired to form layered plaques, but noacute ischemic events are caused. It can be seen that layered plaques represent the unstable characteristics of previous plaques.Optical coherence tomography (OCT) is a high-resolution intracavitary imaging technique that can identify coronary artery layeredplaques in vivo. This article mainly reviews the pathological features, OCT imaging findings, clinical features and treatmentstrategies of coronary artery layered plaques, aiming to improve clinicians' understanding of coronary artery layered plaques.

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