作者：吕若兰，程为平，刘鹏，韩天然

单位：

1.150040黑龙江省哈尔滨市，黑龙江中医药大学第一临床医学院　2.150040黑龙江省哈尔滨市，黑龙江中医药大学附属第一医院针灸二科　3.150040黑龙江省哈尔滨市，黑龙江中医药大学附属第一医院针灸六科

单位（英文）：

1.The First Clinical Medical School, Heilongjiang University of Chinese Medicine, Harbin 150040, China2.Second Department of Acupuncture, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin 150040,China3.Sixth Department of Acupuncture, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin 150040,China

关键词：

动脉粥样硬化；清浊相干；脑心同治；治疗

关键词（英文）：

Arteriosclerosis; Disorder between Qing and Zhuo; Simultaneous treatment of heart and brain; Treatment

中图分类号：

R 543.5

DOI：

10.12114/j.issn.1008-5971.2023.00.188

基金项目：

黑龙江省卫生健康委科研课题（20210303070174）

摘要：

动脉粥样硬化（AS）是心血管疾病的关键发病机制，可导致心肌梗死、心绞痛、缺血性心脏病、缺血性脑卒中等动脉粥样硬化性心血管疾病（ASCVD）的发生。研究表明，与单独使用他汀类药物相比，中药联合他汀类药物治疗AS更有优势。在中医学理论中，AS的病机与“清浊相干”密切相关。本文基于“清浊相干”理论，从“脉损”“脉浊”“脉痹”三个层次阐释AS的病机演变过程，指出脾不升清、胃不降浊是“脉损”的病理基础，升降失常、清浊相干是“脉浊”的病机核心，浊邪害清、气虚血瘀是“脉痹”的“病进”转归；并提出升清降浊、益气活血的治疗总则，同时注重脑心同治同防，这为AS的中医防治提供了新思路。

英文摘要：

Atherosclerosis (AS) is the key pathogenesis of cardiovascular diseases, which can lead to the occurrence ofatherosclerotic cardiovascular disease (ASCVD) such as myocardial infarction, angina pectoris, ischemic heart disease and ischemicstroke. The method of combining traditional Chinese medicine and statins to treat AS is efficacy superior than only stains. In thetheory of traditional Chinese medicine, the pathogenesis of AS is closely related to "Disorder between Qing and Zhuo" . Based onthe theory of "Disorder between Qing and Zhuo" , this paper explains the pathogenesis evolution process of AS from the three levelsof "pulse damage" "pulse turbidity" "pulse arthralgia" , and points out that the pathological basis of "pulse damageis" that thespleen does not rise clear and the stomach does not drop turbidity; the disorder of ascending and descending and the coherence ofclearing and turbidity are the core of the pathogenesis of "pulse turbidity" ; turbid evil harm clear, Qi deficiency and blood stasis is"disease progression" outcome of "pulse arthralgia" . It also puts forward the general principles of treatment of ascending clear anddescending turbidity, benefiting Qi and activating blood circulation, and pays attention to the simultaneous treatment of brain andheart, which provides a new idea for the prevention and treatment of AS in traditional Chinese medicine.

参考文献：