作者：马明明，高小童，张鑫杰，杨丽静

单位：

1.050091河北省石家庄市，河北中医学院 2.050011河北省石家庄市，河北中医学院第一附属医院脑病科 通信作者：杨丽静，E-mail：106100127@qq.com

Units：

1.Hebei University of Chinese Medicine, Shijiazhuang 050091, China 2.Department of Encephalopathy, the First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang 050011,China Corresponding author: YANG Lijing, E-mail: 106100127@qq.com

关键词：

脑梗死; 动脉粥样硬化; 浊毒; 中医病机; 中医药疗法; 综述;

Keywords：

Brain infarction; Atherosclerosis; Turbid toxin; Pathogenesis (TCM) ; Traditional Chinese medicinetherapy; Review

CLC：

DOI：

10.12114/j.issn.1008-5971.2022.00.090

Funds：

摘要：

大动脉粥样硬化型脑梗死是我国最常见的脑梗死亚型,病机复杂,复发率高。近年来基于其病机的中西医研究不断深入。本文结合大动脉粥样硬化型脑梗死“动脉-动脉栓塞、低灌注、穿支动脉受累”等西医病机,回顾了“浊毒”理论的形成过程及基本特点,指出大动脉粥样硬化型脑梗死中医病机为“浊毒伏脉,胶结痰瘀”,提出了“化浊解毒、益气散瘀通络”的治疗原则,并综述了近年来相关中医药治疗研究进展以为此治疗原则提供依据。本文丰富了大动脉粥样硬化型脑梗死的中医病机,为其中医治疗方案的选择提供了更多依据。

Abstract：

【Abstract】 Large atherosclerotic cerebral infarction is the most common subtype of cerebral infarction in China, withcomplex pathogenesis and high recurrence rate. In recent years, the research of traditional Chinese and western medicine basedon its pathogenesis has been deepening. Based on the western medical pathogenesis of large atherosclerotic cerebral infarction,such as "arterial arterial embolism, low perfusion and perforator artery involvement" , this paper reviews the formation process andbasic characteristics of the theory of "turbid toxin" , points out that the TCM pathogenesis of large arterial atherosclerotic cerebralinfarction is "turbid toxin adjoins artery, cement phlegm and blood stasis" , puts forward the treatment principle of "removingturbid toxin, detoxifying Qi, dissipating blood stasis and clearing collaterals" , and reviews the research progress of related TCMtreatment in recent years to provide the basis for this treatment principle. This paper enriches the TCM pathogenesis of large arteryatherosclerotic cerebral infarction, and provides more basis for the selection of TCM treatment program.

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