作者：孙中婷，郭莉莉，魏明翔，柏根基

单位：

1.223300江苏省淮安市，徐州医科大学淮安临床学院 南京医科大学附属淮安第一医院影像科 2.223400江苏省淮安市，涟水县人民医院影像科 通信作者：郭莉莉，E-mail：guolili@163.com 柏根基，E-mail：hybgj0451@163.com

Units：

1.Department of Imaging, Huaian Clinical College of Xuzhou Medical University/the Affiliated Huaian No.1 People's Hospitalof Nanjing Medical University, Huaian 223300, China 2.Department of Imaging, Lianshui County People's Hospital, Huaian 223400, China Corresponding author: GUO Lili, E-mail: guolili@163.com BAI Genji, E-mail: hybgj0451@163.com

关键词：

磁共振成像; 基底动脉; 大脑中动脉; 血管造影术,数字减影; MRI3DT2-SPACE;

Keywords：

Magnetic resonance imaging; Basilar artery; Middle cerebral artery; Angiography, digital subtraction; MRI3D T2-SPACE

CLC：

DOI：

10.12114/j.issn.1008-5971.2022.00.073

Funds：

淮安市卫生健康科研基金面上项目（HAWJ201904）

摘要：

目的 评价MRI 3D T2-SPACE诊断大脑中动脉及基底动脉狭窄的价值。方法 选取2019年11月至2020年10月在南京医科大学附属淮安第一医院就诊的40例脑血管狭窄患者为研究对象,选取符合研究要求的大脑中动脉及基底动脉共120根。在入院1周内完成颅颈动脉MRI 3D T2-SPACE和数字减影血管造影(DSA)检查,分别评估动脉狭窄程度。按狭窄程度分成轻度(1%～49%)、中度(50%～69%)、重度(70%～99%)和闭塞(100%),和金标准DSA检查对照,计算灵敏度、特异度,并分析MRI 3D T2-SPACE和DSA诊断结果的一致性。结果 MRI 3D T2-SPACE诊断大脑中动脉及基底动脉狭窄/闭塞的灵敏度、特异度结果如下,轻度狭窄分别为90.0%、96.4%,中度狭窄分别为77.8%、98.2%,重度狭窄分别为96.7%、97.8%,闭塞分别为87.5%、100.0%。MRI 3D T2-SPACE与DSA检查诊断大脑中动脉及基底动脉轻、中、重度狭窄及闭塞的一致性分别为0.760、0.760、0.934、0.929。结论 MRI 3D T2-SPACE能够较准确地评估大脑中动脉及基底动脉狭窄程度,特别是对重度狭窄及闭塞的诊断与DSA检查结果高度一致,作为血管检查的一种全新技术,其将会在临床发挥重要作用。

Abstract：

【Abstract】 Objective To evaluate the value of MRI 3D T2-SPACE sequence in the diagnosis of middle cerebralartery and basilar artery stenosis. Methods A total of 40 patients with ischemic stroke that admitted to the Affiliated HuaianNo.1 People's Hospital of Nanjing Medical University from November 2019 to October 2020 were collected and a total of 120middle cerebral artery and basilar artery that met research requirements were selected. MRI 3D T2-SPACE and DSA wereperformed within one week after admission to assess the degree of arterial stenosis. According to the degree of stenosis, the patientswere divided into mild (1%-49%) , moderate (50%-69%) , severe (70%-99%) and occlusion (100%). The specificity, sensitivitywere calculated, and consistency of MRI 3D T2-SPACE and DSA diagnosis results were analyzed and evaluated. Results Thesensitivity, specificity of MRI 3D T2-SPACE were 90.0%, 96.4% for mild stenosis, 77.8%, 98.2% for moderate stenosis, 96.7%,97.8% for severe stenosis and 87.5%, 100.0% for occlusion, respectively. The consistency of MRI 3D T2-SPACE and DSA injudging mild, moderate, severe and occlusion of middle cerebral artery and basilar artery stensis were 0.760, 0.760, 0.934 and0.929, respectively. Conclusion MRI 3D T2-SPACE can more accurately assess the degree of stenosis of the middle cerebralartery and basilar artery, especially the diagnosis of severe stenosis and occlusion is highly consistent with the results of DSAexamination. As a new technique for vascular examination, it will play an important role in clinical practice.

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