作者：杨姣，薛艺东，王涛，刘惠芳

单位：

716000 陕西省延安市，延安大学附属医院神经内科；通信作者：薛艺东，E-mail：Xueyidong1988@163.com

Units：

Department of Neurology，Yan'an University Affiliated Hospital，Yan'an 716000，China；Corresponding author：XUE Yidong，E-mail：Xueyidong1988@163.com

关键词：

氟化物中毒；脑疾病，代谢性；氟乙酰胺；杀鼠剂；病例报告；历史文献

Keywords：

Fluoride poisoning；Brain diseases，metabolic；Fluoroacetamide；Rodenticide；Case report；Historical artical

CLC：

R 595.5　R 742.89

DOI：

DOI：10.3969/j.issn.1008-5971.2020.02.019

Funds：

延安市成果转化与推广应用专项项目（2018CGZH-15）

摘要：

氟乙酰胺是一种高效剧毒、残留性强的有机氟杀鼠剂，而氟乙酰胺中毒易导致多种脏器功能损伤，尤其是中枢神经系统损伤，并造成氟乙酰胺中毒性脑病等。本文报道了 1 例急性氟乙酰胺中毒性脑病患者并进行了文献复习，以期提高临床对氟乙酰胺中毒性脑病的认识。

Abstract：

Fluoroacetamide is one kind of organic fluoride rodenticide with highly toxic and highly residual，however，fluoroacetamide poisoning is easy to lead to multiple organ function impairment especially central nervous systeminjury and even fluoroacetamide poisoning encephalopathy. This paper reported a patient with acute fluoroacetamide poisoningencephalopathy and reviewed the relevant literatures，in order to improve the understanding of fluoroacetamide poisoningencephalopathy.

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